Mesenchymal stromal cells-derived extracellular vesicles in cartilage regeneration: potential and limitations
Abstract Background Articular cartilage injuries can lead to pain, stiffness, and reduced mobility, and may eventually progress to osteoarthritis (OA).Despite substantial research efforts, effective therapies capable of regenerating cartilage are still lacking.Mesenchymal stromal cells (MSCs) are known for their differentiation and immunomodulatory